Mobile-Phase Contributions to Organic-Solvent Excess Adsorption and Surface Diffusion in Reversed-Phase Liquid Chromatography

Autor: Andreas Steinhoff, Alexandra Höltzel, Nicole Trebel, Ulrich Tallarek
Rok vydání: 2022
Předmět:
Zdroj: The journal of physical chemistry. B. 126(49)
ISSN: 1520-5207
Popis: Fast transport of retained analytes in reversed-phase liquid chromatography occurs through surface diffusion in the organic-solvent (OS)-enriched interfacial "ditch" region between the hydrophobic stationary phase and the water (W)-OS mobile phase. Through molecular dynamics simulations that recover the OS excess adsorption isotherms of a typical C
Databáze: OpenAIRE