Effect of Experimental Fluorosis on the Surface Topography of Developing Enamel Crystals
| Autor: | R.C. Shore, Steven J. Brookes, Wood, D. A. Smith, Jennifer Kirkham, Mark L. Wallwork, J. Zhang, Colin Robinson |
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| Rok vydání: | 2000 |
| Předmět: |
Male
Fluorosis Dental Surface Properties Dentistry Crystal growth Surface finish Microscopy Atomic Force Crystal chemistry.chemical_compound stomatognathic system Microscopy medicine Surface roughness Animals Rats Wistar Dental Enamel General Dentistry Enamel paint business.industry Chemistry medicine.disease Rats Incisor stomatognathic diseases visual_art visual_art.visual_art_medium Biophysics Sodium Fluoride Crystallization business Fluoride Dental fluorosis |
| Zdroj: | Caries Research. 35:50-56 |
| ISSN: | 1421-976X 0008-6568 |
| DOI: | 10.1159/000047431 |
| Popis: | Dental fluorosis is an increasing problem, yet the precise mechanism by which fluoride exerts its effects remains obscure. In the present study, we have used atomic force microscopy to image and quantitate surface features of enamel crystals isolated from specific developmental stages of fluorotic and control rat incisors. The results showed a significant decrease in crystal surface roughness with development in control tissue. Crystals from fluorotic tissue were significantly rougher than controls at all stages of development, did not decrease in roughness during the later stages of their development and had many morphological abnormalities. These data clearly demonstrate an effect for fluoride on enamel crystal surfaces which could reflect changes in the nature and distribution of growth sites and/or in mineral–matrix interactions. These would be expected to affect crystal growth during maturation, resulting in the characteristic porous appearance of fluorotic lesions in mature teeth. |
| Databáze: | OpenAIRE |
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