Prevalence of human herpesvirus-8 among HIV-infected patients, intravenous drug users and the general population in Iran

Autor: Zabihollah Shoja, Mostafa Haji Mollahoseini, Ahmad Nejati, Rezvan Kakavand-Ghalehnoei, Sayed Mahdi Marashi, Alireza Najafi, Somayeh Jalilvand, Shohreh Shahmahmoodi
Rok vydání: 2015
Předmět:
Zdroj: Sexual health. 13(3)
ISSN: 1448-5028
Popis: Studies looking at the frequency of human herpesvirus-8 (HHV-8) among Iranian blood donors have produced conflicting results. The aim of this study was to investigate the prevalence of HHV-8 DNA by using polymerase chain reaction methods among 168 healthy individuals, 60 intravenous drug users and 100 HIV-infected patients from Iran. The prevalence of HHV-8 was significantly higher among intravenous drug users (13.3%) compared with the general population (3.6%; P = 0.017). The HHV-8 genome was mostly detected among intravenous drug users who displayed high-risk sexual behaviours. Moreover, the HHV-8 genome was also detected in 8% of HIV-infected patients. The present study findings support the likelihood that the transmission of HHV-8 is via a sexual route in the Iranian population.
Databáze: OpenAIRE