Bronchiectasis in a patient with CREST syndrome
| Autor: | Bruno Fautrel, Koeger Ac, Pierre Bourgeois, Sylvie Rozenberg, Anne Coutaux, Frédéric Lavie |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
CREST Syndrome
Pathology medicine.medical_specialty Scleroderma Fatal Outcome Rheumatology Lower respiratory tract infection medicine Humans Cyclophosphamide Aged Bronchiectasis Lung business.industry medicine.disease Dermatology Pathophysiology medicine.anatomical_structure Concomitant Prednisone Female Radiography Thoracic Tomography X-Ray Computed Vasculitis business Immunosuppressive Agents |
| Zdroj: | Joint Bone Spine. 69:515-518 |
| ISSN: | 1297-319X |
| DOI: | 10.1016/s1297-319x(02)00441-4 |
| Popis: | Bronchiectasis is an uncommon pulmonary manifestation of systemic sclerosis (SSc). We report the case of a 70-year-old woman with CREST syndrome and vasculitis who developed multifocal symptomatic bronchiectasis. The bronchiectasis and immunosuppressive therapy precipitated severe lower respiratory tract infection, which was fatal within a few months. The concomitant occurrence of bronchiectasis and SSc raises the possibility of a pathophysiological relationship. Several hypotheses can be put forward to explain the occurrence of bronchial wall damage leading to bronchiectasis. Whatever the mechanism, cases of bronchiectasis in patients with SSc should be reported to make physicians aware of the substantial risk associated with this combination. |
| Databáze: | OpenAIRE |
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