A longitudinal follow-up of bacterial vaginosis during pregnancy

Autor: Eira Andersson, Jens Jörgen Platz-Christensen, BjÖrn Hagmar, Åke Brandberg, Nils Wiqvist, Peter Pernevi
Rok vydání: 1993
Předmět:
Zdroj: Acta Obstetricia et Gynecologica Scandinavica. 72:99-102
ISSN: 1600-0412
0001-6349
DOI: 10.3109/00016349309023420
Popis: Bacterial vaginosis (BV) has been considered by many investigators to be a risk factor for preterm labor. We have followed vaginal pH and the persistence of clue cells in Papanicolaou stained smears in 119 pregnant women during the course of pregnancy. Of 19 patients with clue cells in their smears during the first trimester, 11 (58%) still had clue cells at the second visit during the third trimester. Of the 100 patients without clue cells during their first trimester, none exhibited clue cells during the third trimester. If the persistence of clue cells is truly a risk factor for adverse pregnancy outcome, screening in the first trimester would identify a risk group of 15%. This risk group diminishes to 9% at the time of the third trimester. Vaginal pH > 4.5 had a recovery sensitivity of 76% and specificity of 83%. If clue cells can be considered as the identifying standard for bacterial vaginosis, the sensitivity and specificity of pH is 89% and 94%, respectively. The establishment of the diagnosis of BV during pregnancy and, in some cases, the treatment of the condition may be important as routine procedures in the antenatal center.
Databáze: OpenAIRE