Neurological presentations of Bartonella henselae infection
Autor: | J C García García, Iria Cabo-López, F J Cores, Matilde Trigo, Alfredo Puy-Núñez, A P Suárez-Gil, Beatrice Canneti, A Rodriguez-Regal |
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Rok vydání: | 2018 |
Předmět: |
Bartonella
Adult Male medicine.medical_specialty Neurology Adolescent Fundus Oculi medicine.medical_treatment Dermatology 03 medical and health sciences Young Adult 0302 clinical medicine Internal medicine Epidemiology medicine Humans Optic neuritis 030212 general & internal medicine Aged Retrospective Studies Bartonella henselae biology business.industry Aseptic meningitis Cat-Scratch Disease Cat-scratch disease Immunosuppression General Medicine Middle Aged medicine.disease biology.organism_classification Anti-Bacterial Agents Psychiatry and Mental health Treatment Outcome Female Neurology (clinical) business 030217 neurology & neurosurgery |
Zdroj: | Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 40(2) |
ISSN: | 1590-3478 |
Popis: | Neurological symptoms in patients with cat-scratch disease (CSD) have been rarely reported. The aim of this study is to analyze the frequency of neurological CSD (NCSD) and describe the disease clinical presentation, management and outcome. We retrospectively selected patients with a CSD syndrome and Bartonella IgG titers > 1:256. Data regarding epidemiological, clinical, management, and follow-up features were analyzed and discussed. A comparison between NCSD and non-neurological CSD (NNCSD) was established. Thirty-nine CSD patients were selected. NCSD frequency was 10.25%. No children were found affected in the NCSD group. A 65.7% of NNCSD and the entirety of the NCSD group had a history of cat exposure. Immunosuppression was only present in the NNCSD group (8.6%). NCSD presentations were as follows: isolated aseptic meningitis (25%), neuroretinitis (50%), and isolated optic neuritis (25%). A greater proportion of patients in the NCSD group had fever and raised levels of acute phase reactants and white blood cells. 85.7% of NNCSD had a complete recovery, whereas only 50% of the NCSD patients experienced a full recovery. NCSD may be a distinctive group compared to NNCSD due to its later age of presentation, the more intense systemic response, and the poorer outcome. |
Databáze: | OpenAIRE |
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