Sclerosing polycystic adenosis of parotid gland with dysplasia and ductal carcinoma in situ
| Autor: | Roderick H.W. Simpson, M. Pfaltz, A. Skálová, Michal Michal, J. Přádná, Ivo Stárek |
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| Rok vydání: | 2002 |
| Předmět: |
Adult
In situ Pathology medicine.medical_specialty Pathology and Forensic Medicine Pathogenesis Humans Medicine Child Receptor Molecular Biology business.industry Carcinoma in situ Carcinoma Ductal Breast Cell Biology General Medicine Ductal carcinoma medicine.disease Immunohistochemistry Parotid Neoplasms Parotid gland Microscopy Electron medicine.anatomical_structure Dysplasia Female business Precancerous Conditions Carcinoma in Situ |
| Zdroj: | Virchows Archiv. 440:29-35 |
| ISSN: | 1432-2307 0945-6317 |
| DOI: | 10.1007/s004280100481 |
| Popis: | We describe three cases of sclerosing polycystic adenosis (SPA) of the parotid gland, a salivary condition analogous to fibrocystic disease of the breast. For the first time, immunoreactivity for oestrogen and progesterone receptors was demonstrated, suggesting a possible participation of hormone stimulation in its pathogenesis. In addition, all our cases showed foci of dysplasia of the ductal epithelium, which in one case was severe enough to amount to carcinoma in situ. This feature that has not previously been reported in SPA. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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