Combined Coronary Artery Bypass Graft (CABG) Surgery and Lung Resection for Lung Cancer in Patients More than 50 Years-of-Age
| Autor: | Yiwei Pu, Zilun Wei, Chao Chen, Ban Liu, Chang Gu, Qianfan Li, Yu Lin, Yangyang Zhang, Zhi Li, Jingjing Liu |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Operations Research Lung Neoplasms medicine.medical_treatment Coronary Artery Bypass Off-Pump Kaplan-Meier Estimate 030204 cardiovascular system & hematology Metastasis 03 medical and health sciences 0302 clinical medicine Postoperative Complications Clinical Research medicine Humans Myocardial infarction Lung cancer Aged Aged 80 and over Chemotherapy business.industry Retrospective cohort study General Medicine Perioperative Middle Aged medicine.disease Surgery medicine.anatomical_structure Treatment Outcome Median sternotomy 030220 oncology & carcinogenesis Female Morbidity business Artery Follow-Up Studies |
| Zdroj: | Medical Science Monitor : International Medical Journal of Experimental and Clinical Research |
| ISSN: | 1643-3750 1234-1010 |
| Popis: | BACKGROUND The co-existence of coronary heart disease (CHD) and lung cancer is increasing in an increasingly aging population. The aim of this study was to evaluate patient outcome from combined off-pump coronary artery bypass graft (CABG) surgery and lung resection in patients more than 50 years-of-age. MATERIAL AND METHODS A retrospective clinical study of 23 patients with a mean age of 70.2±8.4 years (range, 51-86 years) included 18 men and five women with CHD and lung cancer who underwent a single operation with combined off-pump CABG surgery and lung resection, for non-small cell lung cancer (NSCLC) (n=22) and small cell lung cancer (n=1). Surgical approaches included: median sternotomy in six patients; left lateral thoracotomy in nine patients; a median sternotomy in three patients; median sternotomy combined with thoracoscopic lobectomy in five patients. RESULTS In the retrospective study of 23 patients, there were no deaths and no new cases of myocardial infarction (MI) in the immediate perioperative period. During the follow-up period, six patients died from lung cancer metastasis or recurrence; one patient died of acute renal failure; and one patient died from the effects of chemotherapy. The remaining 15 patients underwent postoperative follow-up for between 3-79 months with no deaths and no new cases of MI. CONCLUSIONS For patients who are more than 50 years-of-age and who have CHD and lung cancer, a single combined operation that includes off-pump CABG and lung resection can be safe and effective. |
| Databáze: | OpenAIRE |
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