Identification and characterization of c-Jun-N-terminal phosphorylation as an epigenetic regulator of highly methylated gene promoter regions in glioblastoma multiforme

Autor:	Heiland, DH, Ferrarese, R, Dai, F, Claus, R, Masilamani, A, Unterkircher, T, Fedele, V, Bug, E, Carro, MS, Weyerbrock, A
Jazyk:	angličtina
Rok vydání:	2014
Předmět:	glioblastoma multiforme ddc: 610 epigenetics methylation 610 Medical sciences Medicine
Zdroj:	65. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC); 20140511-20140514; Dresden; DOCMO.10.03 /20140513/
DOI:	10.3205/14dgnc055
Popis:	Objective: High-grade gliomas (HGG) are the most common brain tumors with an average survival of 14 months. A large number of highly methylated gene loci (G-CIMP) are associated with the proneural subgroup and better clinical outcome. Our aim was to identify and characterize putative transcription factors[for full text, please go to the a.m. URL] 65. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)
Databáze:	OpenAIRE
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