Analysis of the Diurnal Intraocular Pressure Profile Pre and Post Trabeculectomy using 24-Hour Monitoring of Intraocular Pressure
| Autor: | Thomas E. Jackson, Michael S. Wertheim, Paul G. D. Spry, John M Sparrow, Adam H. Ross, Jeremy P. Diamond |
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| Rok vydání: | 2010 |
| Předmět: |
Adult
Male Study groups Intraocular pressure medicine.medical_specialty genetic structures Mitomycin medicine.medical_treatment Glaucoma Trabeculectomy Preoperative care Diurnal fluctuation Tonometry Ocular Young Adult Ophthalmology Preoperative Care medicine Humans Low Tension Glaucoma Pre and post Intraocular Pressure Aged Monitoring Physiologic Aged 80 and over Postoperative Care Medical treatment business.industry General Medicine Middle Aged medicine.disease eye diseases Circadian Rhythm Female Fluorouracil sense organs business Glaucoma Open-Angle Follow-Up Studies |
| Zdroj: | European Journal of Ophthalmology. 21:400-403 |
| ISSN: | 1724-6016 1120-6721 |
| DOI: | 10.5301/ejo.2010.5821 |
| Popis: | Purpose TO compare the diurnal intraocular pressure (IOP) profile pre and post trabeculectomy with a control group of medically controlled patients. We compared the change in mean, peak, and diurnal IOP fluctuation. Methods This was an observational study of patients at the Bristol Eye Hospital, United Kingdom. All patients underwent initial and subsequent phasing, with surgery between for cases. The unpaired Student t test compared the changes (initial - subsequent) in mean, peak, and fluctuation between cases and controls. Results Fifteen eyes underwent trabeculectomy surgery while the control group contained 17 eyes controlled on topical medical treatment. There was a statistically significant reduction in both mean IOP of 3.7 mmHg (p=0.002) and peak IOP of 4.4 mmHg (p=0.025) in the surgical group compared to the medical group. There was no statistically significant change in the IOP fluctuation between the 2 study groups (p=0.296). Conclusions There is a significant reduction in mean IOP and peak IOP following trabeculectomy. We showed no statistically significant change in the diurnal fluctuation of IOP following trabeculectomy. |
| Databáze: | OpenAIRE |
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