Herbex-Kid Inhibits Immediate Hypersensitivity Reactions in Mice and Rats
| Autor: | Solomon F. Emerson, Rawal Prasad, Suresh Bhojraj, Nanjan Mulla Jogge, S. Prabakar, Anil Kumar |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
Contraction (grammar)
Pharmacology chemistry.chemical_compound Herbex-kid medicine Original Articles - Basic Science Receptor antiallergic biology business.industry Degranulation mast cell stabilization lcsh:Other systems of medicine medicine.disease lcsh:RZ201-999 Type I hypersensitivity reaction Ovalbumin Complementary and alternative medicine chemistry Immunology biology.protein Itching medicine.symptom business Histamine Anaphylaxis Type I hypersensitivity |
| Zdroj: | Evidence-Based Complementary and Alternative Medicine, Vol 5, Iss 3, Pp 289-294 (2008) Evidence-based Complementary and Alternative Medicine : eCAM |
| ISSN: | 1741-4288 |
| Popis: | Herbex-kid (HK), a polyherbal formulation was evaluated in various experimental allergic models of Type I hypersensitivity reactions. Compound 48/80 (C 48/80) has been shown to induce rat mesentery mast cell degranulation and HK (1.07, 10.75 and 107.5 mg ml−1) inhibited the mast cell degranulation in a dose dependent manner. HK (1.07, 10.75 and 107.5 mg kg−1; p.o.) showed dose-dependent protection against C 48/80 induced systemic anaphylaxis in male Balb/C mice. In active anaphylaxis model, male Wistar rats orally administered with 10.75 and 107.5 mg kg−1of HK showed significant (P −1showed significant (P −1it showed significant (P P |
| Databáze: | OpenAIRE |
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