Intra-articular morphine and postoperative analgesia after knee arthroscopy
| Autor: | I.G Vlachonikolis, G Anthopoulos, N.S. Gavalas, G.I. Drosos, A.N. Papoutsidakis |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Visual analogue scale medicine.medical_treatment Group B Injections Intra-Articular law.invention Arthroscopy Double-Blind Method Randomized controlled trial law medicine Humans Knee Orthopedics and Sports Medicine Prospective Studies Prospective cohort study Saline Pain Measurement Pain Postoperative Dose-Response Relationship Drug Morphine medicine.diagnostic_test business.industry Surgery Analgesics Opioid Anesthesia Hyperalgesia Female medicine.symptom business medicine.drug |
| Zdroj: | The Knee. 9:335-340 |
| ISSN: | 0968-0160 |
| DOI: | 10.1016/s0968-0160(02)00074-1 |
| Popis: | The aim of this study was to evaluate the postoperative analgesic effect of intra-articular administration of a low- and a high-dose morphine solution after knee arthroscopy. Thirty patients who underwent diagnostic arthroscopy or arthroscopic meniscectomy were allocated in three groups. At the end of the arthroscopic procedure patients in Group A received intra-articularly 20 ml normal saline (N/S), Group B received 5 mg morphine in 20 ml N/S and Group C received 15 mg morphine in 20 ml N/S. The postoperative pain was assessed using a visual analogue scale for 24 h, while all the patients stayed at hospital. Side effects from the central action of opioids were not detected. Although the pain scores in the group of low-dose morphine were lower than in the control group, we failed to detect any significant differences in pain scores among the three groups. There was evidence that a high-dose can cause hyperalgesia. |
| Databáze: | OpenAIRE |
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