Treatment of Focal Segmental Glomerulosclerosis Recurrence in the Renal Allograft: A Report of Two Cases
| Autor: | Philip M. Carpenter, Clarence E. Foster, Whitney Pasch, Minh-Ha Tran, Cynthia Chan, Hirohito Ichii |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Pathology
medicine.medical_specialty Renal allograft medicine.medical_treatment 030232 urology & nephrology Urology Focal segmental glomerulosclerosis 030230 surgery urologic and male genital diseases Kidney transplantation 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Therapeutic plasma exchange Complications of kidney transplantation Biopsy Medicine and Health Sciences Medicine Creatinine Proteinuria medicine.diagnostic_test business.industry urogenital system Intravenous immune globulin medicine.disease female genital diseases and pregnancy complications 3. Good health chemistry Nephrology Published online: March 2016 Plasmapheresis Rituximab Azotemia medicine.symptom business medicine.drug |
| Zdroj: | Tran, Minh-Ha; Chan, Cynthia; Pasch, Whitney; Carpenter, Philip; Ichii, Hirohito; & Foster, Clarence. (2016). Treatment of Focal Segmental Glomerulosclerosis Recurrence in the Renal Allograft: A Report of Two Cases. Case Reports in Nephrology and Dialysis, 6(1), 53-60. doi: 10.1159/000445428. UC Irvine: Institute for Clinical and Translational Science. Retrieved from: http://www.escholarship.org/uc/item/4wg2c8qn Case Reports in Nephrology and Dialysis |
| DOI: | 10.1159/000445428. |
| Popis: | Focal segmental glomerulosclerosis (FSGS) causes glomerular lesions that can progress to end-stage renal disease. It is suspected to be caused by a circulating factor that is amenable to plasmapheresis removal and exhibits a risk for recurrence in the renal allograft. We present two patients with FSGS recurrence in their allograft kidneys diagnosed by biopsy after significant proteinuria developed in the posttransplant setting. Treatment with therapeutic plasma exchange induced long-term remission in both patients. Spot urine protein:creatinine ratios were monitored and treatment was continued until a target of |
| Databáze: | OpenAIRE |
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