Differential effects of endogenous lithium on neurobehavioural functioning: A study on auditory evoked potentials
Autor: | Hanns Jürgen Kunert, Christine Norra, Gerhard Andreas Wiesmüller, Johanna Feilhauer |
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Rok vydání: | 2010 |
Předmět: |
Adult
Male medicine.medical_specialty Psychometrics Lithium (medication) medicine.drug_class Emotions Population Lithium Serotonergic Mass Spectrometry Statistics Nonparametric Young Adult 03 medical and health sciences Sex Factors 0302 clinical medicine Reaction Time medicine Humans Psychiatry education Biological Psychiatry Depression (differential diagnoses) education.field_of_study Electroencephalography Mood stabilizer medicine.disease Healthy Volunteers 030227 psychiatry 3. Good health Psychiatry and Mental health Acoustic Stimulation Evoked Potentials Auditory Anxiety Female medicine.symptom Psychology Somatization 030217 neurology & neurosurgery Psychoacoustics medicine.drug Clinical psychology |
Zdroj: | Psychiatry Research. 178:176-181 |
ISSN: | 0165-1781 |
DOI: | 10.1016/j.psychres.2009.04.021 |
Popis: | Lithium occurs naturally in food and water. Low environmental concentrations in drinking water are associated with mental illnesses and behavioural offences, and at therapeutic dosages it is used to treat psychiatric (especially affective) disorders, partly by facilitating serotonergic (5-HT) neurotransmission. As little is known about the psychophysiological role of nutritional lithium in the general population, endogenous lithium concentrations were hypothesised to be associated with measurable effects on emotional liability and the loudness dependence (LD) that is proposed as one of the most valid indicators of 5-HT neurotransmission. Auditory evoked potentials of healthy volunteers [N=36] with high (>2.5 microg/l) or low ( |
Databáze: | OpenAIRE |
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