Differential effects of endogenous lithium on neurobehavioural functioning: A study on auditory evoked potentials

Autor: Hanns Jürgen Kunert, Christine Norra, Gerhard Andreas Wiesmüller, Johanna Feilhauer
Rok vydání: 2010
Předmět:
Zdroj: Psychiatry Research. 178:176-181
ISSN: 0165-1781
DOI: 10.1016/j.psychres.2009.04.021
Popis: Lithium occurs naturally in food and water. Low environmental concentrations in drinking water are associated with mental illnesses and behavioural offences, and at therapeutic dosages it is used to treat psychiatric (especially affective) disorders, partly by facilitating serotonergic (5-HT) neurotransmission. As little is known about the psychophysiological role of nutritional lithium in the general population, endogenous lithium concentrations were hypothesised to be associated with measurable effects on emotional liability and the loudness dependence (LD) that is proposed as one of the most valid indicators of 5-HT neurotransmission. Auditory evoked potentials of healthy volunteers [N=36] with high (>2.5 microg/l) or low (
Databáze: OpenAIRE