Synthesis and biological activity of phenoxyphenyl oxamic acid derivatives related to L-thyronine
| Autor: | Jong M. Wasvary, Zouhair F. Stephan, James L. Stanton, Steele Ronald Edward, Ronald Dotson, Edna Cahill, Jenny Tan, Hollis C. Tomaselli |
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| Rok vydání: | 2000 |
| Předmět: |
Stereochemistry
medicine.drug_class Carboxylic acid Clinical Biochemistry Pharmaceutical Science Carboxamide In Vitro Techniques Biochemistry Chemical synthesis chemistry.chemical_compound In vivo Drug Discovery medicine Thyronines Animals Phenols Molecular Biology chemistry.chemical_classification Oxamic Acid Chemistry Anticholesteremic Agents Organic Chemistry Biological activity Cardiovascular Agents In vitro Rats Thyronine Molecular Medicine |
| Zdroj: | Bioorganicmedicinal chemistry letters. 10(15) |
| ISSN: | 0960-894X |
| Popis: | The synthesis of substituted phenoxyphenyl oxamic acid derivatives related to l -thyronine ( l -T3) is described. The in vitro and in vivo cholesterol lowering and cardiovascular effects of these compounds are presented and discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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