Triterpenoid saponins from the fruits and galls of Sapindus mukorossi

3)-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranoside], sapinmusaponin L (2) [hederagenin-3-O-(4-O-acetyl-alpha-L-arabinopyranosyl)-(1-->3)-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabino-pyranoside], sapinmusaponin M (3) [hederagenin-3-O-(2,3-O-diacetyl-beta-D-xylopyranosyl)-(1-->3)-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranoside], sapinmusaponin N (4) [hederagenin-3-O-(2,4-O-diacetyl-beta-D-xylopyranosyl)-(1-->3)-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranoside], sapinmusaponin O (5) [3,7,20(S)-trihydroxydammar-24-ene-3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-glucopyranoside], and sapinmusaponin P (6) [3,7,20(R)-trihydroxydammar-24-ene-3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-d-glucopyranoside], along with seven known saponins (7-13), were isolated from fruits and the galls of Sapindus mukorossi. Their structures were elucidated by 1D and 2D NMR spectroscopic techniques and acid hydrolysis. Biological evaluation indicated that saponins 1-4 and 7-13 showed moderate cytotoxicity against several human tumor cell lines. -->

ISSN:	0031-9422
Přístupová URL adresa:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::668acceb5bc56c1d8aa67a3859c85bde https://doi.org/10.1016/j.phytochem.2007.10.033
Rights:	CLOSED
Přírůstkové číslo:	edsair.doi.dedup.....668acceb5bc56c1d8aa67a3859c85bde
Autor:	Chia Ching Liaw, Ming Der Wu, Sin Chung Liao, Li-Chuan Hsu, Hui-Chi Huang, Yang Chang Wu, Yao-Haur Kuo, Wei Jern Tsai
Rok vydání:	2008
Předmět:	chemistry.chemical_classification Magnetic Resonance Spectroscopy Molecular Structure biology Stereochemistry Saponin Plant Science General Medicine Nuclear magnetic resonance spectroscopy Saponins Horticulture Sapindaceae biology.organism_classification Sapindus Biochemistry Triterpenes Terpenoid Human tumor Triterpenoid chemistry Triterpene Fruit Sapindus mukorossi Molecular Biology
Zdroj:	Phytochemistry. 69:1609-1616
ISSN:	0031-9422
Popis:	Six saponins, sapinmusaponin K (1) [hederagenin-3-O-(3-O-acetyl-alpha-L-arabinopyranosyl)-(1-->3)-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranoside], sapinmusaponin L (2) [hederagenin-3-O-(4-O-acetyl-alpha-L-arabinopyranosyl)-(1-->3)-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabino-pyranoside], sapinmusaponin M (3) [hederagenin-3-O-(2,3-O-diacetyl-beta-D-xylopyranosyl)-(1-->3)-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranoside], sapinmusaponin N (4) [hederagenin-3-O-(2,4-O-diacetyl-beta-D-xylopyranosyl)-(1-->3)-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranoside], sapinmusaponin O (5) [3,7,20(S)-trihydroxydammar-24-ene-3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-glucopyranoside], and sapinmusaponin P (6) [3,7,20(R)-trihydroxydammar-24-ene-3-O-alpha-L-rhamnopyranosyl-(1-->2)-beta-d-glucopyranoside], along with seven known saponins (7-13), were isolated from fruits and the galls of Sapindus mukorossi. Their structures were elucidated by 1D and 2D NMR spectroscopic techniques and acid hydrolysis. Biological evaluation indicated that saponins 1-4 and 7-13 showed moderate cytotoxicity against several human tumor cell lines.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::668acceb5bc56c1d8aa67a3859c85bde https://doi.org/10.1016/j.phytochem.2007.10.033 Zobrazit plný text záznamu Full Text from ScienceDirect