Comparison of Successful Myocardial Reperfusion and Adverse Events in Patients With ST-Elevation Myocardial Infarction Who Underwent Rescue Percutaneous Coronary Intervention After Failed Fibrinolytic Therapy With Versus Without Manual Coronary Thrombus Aspiration
Autor: | Ahmed Mohamed Boghdady, Mahmoud I. Elbadry |
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Rok vydání: | 2015 |
Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Myocardial Infarction Salvage therapy Myocardial Reperfusion Suction Coronary Angiography Percutaneous Coronary Intervention Coronary thrombosis Internal medicine Fibrinolysis medicine Humans Thrombolytic Therapy Prospective Studies cardiovascular diseases Myocardial infarction Aged Thrombectomy Salvage Therapy business.industry Coronary Thrombosis Percutaneous coronary intervention Middle Aged medicine.disease Combined Modality Therapy Treatment Outcome Conventional PCI Cardiology Female Stents Myocardial infarction diagnosis Cardiology and Cardiovascular Medicine business Mace |
Zdroj: | The American Journal of Cardiology. 116:1185-1192 |
ISSN: | 0002-9149 |
Popis: | It has been unclear the impact of manual thrombus aspiration (TA) on procedural outcomes in patients with ST-elevation myocardial infarction (STEMI) who underwent rescue percutaneous coronary intervention (PCI) after failed fibrinolytic therapy in comparison with primary PCI. Our aim was to test the hypothesis that manual TA may improve myocardial reperfusion and clinical outcomes in patients with STEMI who underwent rescue PCI after failed fibrinolytic therapy. From March 2011 to March 2014, 70 patients with STEMI after unsuccessful fibrinolysis were randomized to either rescue PCI with TA (TA group) or without TA (NTA group). Primary end points were rate of myocardial blush grade ≥2 and ST-segment resolution ≥70%. The secondary end point included 30 days follow-up for major adverse cardiac events (MACEs). Baseline clinical and angiographic characteristics were similar in the 2 groups. The TA and NTA groups were compared as follows: myocardial blush grade ≥2, 71% versus 46% (p |
Databáze: | OpenAIRE |
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