Predictive role of preoperative lymphoscintigraphy on the status of the sentinel lymph node in clinically node-negative patients with cutaneous melanoma

Autor: Carmine Di Somma, Nicola Solari, Francesco Cardinale, Mattia Stella, M. Gipponi, Marina Gualco, Paola Queirolo, Giuseppe Villa, Ferdinando Cafiero, Arnoldo Piccardo
Rok vydání: 2009
Předmět:
Adult
Male
Cancer Research
medicine.medical_specialty
Skin Neoplasms
Sentinel lymph node
Dermatology
Metastasis
Preoperative Care
80 and over
Humans
Medicine
Stage (cooking)
Radionuclide Imaging
Melanoma
Technetium Tc 99m Aggregated Albumin
Pathological
Lymph node
Aged
Retrospective Studies
Aged
80 and over

Frozen section procedure
Intraoperative Care
pathology/radionuclide imaging/secondary/surgery
Sentinel Lymph Node Biopsy
business.industry
physiology/radionuclide imaging/surgery
diagnosis/radionuclide imaging
Middle Aged
medicine.disease
Tumor Burden
pathology/radionuclide imaging/surgery
medicine.anatomical_structure
Oncology
Adult
Aged
Aged

80 and over
Female
Humans
Intraoperative Care
Lymph Node Excision
Lymph Nodes

physiology/radionuclide imaging/surgery
Lymphatic Metastasis

diagnosis/radionuclide imaging
Male
Melanoma

pathology/radionuclide imaging/secondary/surgery
Middle Aged
Preoperative Care
Retrospective Studies
Sentinel Lymph Node Biopsy
Skin Neoplasms

pathology/radionuclide imaging/surgery
Technetium Tc 99m Aggregated Albumin

diagnostic use
Tumor Burden

Lymphatic Metastasis
Cutaneous melanoma
Lymph Node Excision
Female
Lymph Nodes
Radiology
diagnostic use
business
Zdroj: Melanoma Research. 19:243-251
ISSN: 0960-8931
Popis: We reviewed our experience to assess the predictive role of preoperative lymphoscintigraphy with regard to the pathological status of sentinel lymph node (sN) in patients with cutaneous melanoma, to optimize the surgical treatment planning with regard to the use of intraoperative frozen section examination of sN. Eighty-eight patients with clinically node-negative cutaneous melanoma pT1b-T4 stage underwent preoperative lymphoscintigraphy for the lymphatic mapping of sN. A lymphoscintigraphic 'score' (from L1 to L5) was developed based on the ratio of radiotracer concentration within sN nodes as compared with the injection site. Our score allowed us to foresee that sN of patients with thick melanomas (T3 and T4) and a low preoperative score (L1-L2-L3) had a 90% expected likelihood (P
Databáze: OpenAIRE