Decompensated alcohol related liver disease: acute management
| Autor: | Kieran J Moriarty, Stuart McPherson, Michael R. Lucey |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Pediatrics Cirrhosis 03 medical and health sciences Liver disease 0302 clinical medicine Liver Cirrhosis Alcoholic Ascites medicine Humans Decompensation 030212 general & internal medicine Liver Diseases Alcoholic Cause of death Hepatitis Alcoholic business.industry Acute kidney injury Disease Management Bacterial Infections General Medicine Acute Kidney Injury Jaundice medicine.disease Surgery Alcoholism 030211 gastroenterology & hepatology Liver function medicine.symptom business |
| Zdroj: | BMJ. :i124 |
| ISSN: | 1756-1833 |
| DOI: | 10.1136/bmj.i124 |
| Popis: | What you need to know Alcohol related liver disease (ARLD) and liver cirrhosis are complications of long term excessive alcohol use and occur in 10-20% of chronic, heavy drinkers.1 2 Complications, including hepatic decompensation, variceal bleeding, and hepatocellular carcinoma, reduce life expectancy.1 3 Since 1970, there has been a 400% increase in liver related (mainly alcohol related) deaths across all ages in the UK (fig 1⇓).4 5 Liver disease is now the fifth commonest cause of death in the UK. The average age of death from ARLD is 59 years.6 Fig 1 Standardised mortality data for major causes of death in UK, 1970-2010. Reproduced with permission of Nick Sheron In a report of UK hospitals only 47% of patients received “good” hospital care.7 This review provides guidance on the management of patients with decompensated ARLD, focusing on the first 24 hours after hospital admission. Figure 2⇓ provides a summary of the clinical course of ARLD. Decompensation of cirrhosis occurs when liver function deteriorates, and the disease presents with jaundice … |
| Databáze: | OpenAIRE |
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