Hyponatremia, Hypokalemia, and Fragility Fractures in Old Patients: More than an Association?
| Autor: | Laura Anna Maria Schiara, Elena Grosso, Giovanni Carlo Isaia, Patrizia D'Amelio, Michela Tibaldi, Massimiliano Massaia, Giovenale Moirano, Carlotta Vezza, Elena Spertino, Lorenzo Richiardi |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Endocrinology Diabetes and Metabolism medicine.medical_treatment Osteoporosis Knee replacement 030209 endocrinology & metabolism Hypokalemia 03 medical and health sciences 0302 clinical medicine Endocrinology Risk Factors Internal medicine medicine Humans Orthopedics and Sports Medicine Myocardial infarction Femur Prospective Studies Prospective cohort study Aged Retrospective Studies business.industry Mortality rate Sodium Retrospective cohort study medicine.disease Fracture Hyponatremia Potassium Creatinine 030101 anatomy & morphology medicine.symptom business Osteoporotic Fractures |
| Zdroj: | Calcified tissue international. 106(6) |
| ISSN: | 1432-0827 |
| Popis: | Hyponatremia and hypokalemia are common among elderly and have been associated with osteoporosis, we evaluate the role of these electrolytes as risk for fragility fractures. This study is divided in two parts: one retrospective and one prospective. We retrospectively collected data on urgently admitted patients for femoral fragility fractures (Fx) or for acute myocardial infarction (AMI), and patients admitted for elective hip/knee replacement surgery for osteoarthrosis (OA). Age, sex, serum sodium, potassium, creatinine, and comorbidities were recorded. We enrolled prospectively in-patients from our unit: age, sex, comorbidities, drugs, and fragility fractures were recorded. Blood electrolytes were measured. Cognitive function, nutrition, muscular strength, and balance were evaluated by standard tests. The mortality rate was recorded with a follow-up after hospital discharge. The retrospective study included 2166 subjects: 702 Fx and 1464 controls (907 AMI, 557 OA): the prevalence of hyponatremia was similar in Fx and AMI, whereas it was higher in Fx with respect to OA (p |
| Databáze: | OpenAIRE |
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