A novel approach to assess body composition in children with obesity from density of the fat-free mass
| Autor: | Desirée Gutiérrez-Marín, Judit Muñoz-Hernando, Natàlia Ferré, Ana M. Alejos, Raquel Monné-Gelonch, Joaquin Escribano, Mireia Alcázar, Michelle C. Venables, Mercè Núñez-Roig, Albert Feliu, Ricardo Closa-Monasterolo, Veronica Luque, Mariona Gispert-Llauradó, Jonathan C. K. Wells, Josep Basora, Priya Singh, Carme Rubio-Torrents, Marta Zaragoza-Jordana |
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| Rok vydání: | 2021 |
| Předmět: |
Male
0301 basic medicine Pediatric Obesity Validation study Adolescent 030209 endocrinology & metabolism Critical Care and Intensive Care Medicine Age and sex Body Mass Index Fat mass 03 medical and health sciences 0302 clinical medicine Bias Fat free mass Statistics medicine Cluster Analysis Humans Plethysmograph Child Randomized Controlled Trials as Topic 030109 nutrition & dietetics Nutrition and Dietetics Anthropometry business.industry Reproducibility of Results medicine.disease Obesity Plethysmography Cross-Sectional Studies Adipose Tissue Body Composition Constant density Female business Body mass index |
| Zdroj: | Clinical Nutrition. 40:1102-1107 |
| ISSN: | 0261-5614 |
| DOI: | 10.1016/j.clnu.2020.07.011 |
| Popis: | Summary Background & aims Assessment of Fat Mass (FM) and fat-free mass (FFM) using Air-displacement plethysmography (ADP) technique assumes constant density of FFM (DFFM) by age and sex. It has been recently shown that DFFM further varies according to body mass index (BMI), meaning that ADP body composition assessments of children with obesity could be biased if DFFM is assumed to be constant. The aim of this study was to validate the use of the calculations of DFFM (rather than constant density of the FFM) to improve accuracy of body composition assessment in children with obesity. Methods cross-sectional validation study in 66 children with obesity (aged 8–14 years) where ADP assessments of body composition assuming constant density (FFMBODPOD and FMBODPOD) were compared to those where DFFM was adjusted in relation to BMI (FFMadjusted and FMadjusted), and both compared to the gold standard reference, the 4-component model (FFM4C and FM4C). Results FFMBODPOD was overestimated by 1.50 kg (95%CI -0.68 kg, 3.63 kg) while FFMadjusted was 0.71 kg (−1.08 kg, 2.51 kg) (percentage differences compared to FFM4C were 4.9% (±2.9%) and 2.8% (±2.1%), respectively (p Conclusions The use of constant values for fat-free mass properties may increase bias when assessing body composition (FM and FFM) in children with obesity by two-component techniques such as ADP. Using adjusted corrections as proposed in the present work may reduce the bias by half. |
| Databáze: | OpenAIRE |
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