| Autor: |
Alex Toker, Steven P. Balk, Xin Yuan, Y. Rebecca Chin |
| Rok vydání: |
2023 |
| Popis: |
PDF file 1017K, Figure S1 shows the functions of Akt1 and Akt2 in the proliferation and migration of prostate tumor cells. Figure S2 demonstrates that all three Akt isoforms play a critical role in MDA-MB-468 breast cancer cell proliferation and formation of tumor spheroids. Figure S3 shows that Akt2 does not play a critical role in the survival of tumor cells with wild-type PTEN. Figure S4 shows the expression and phosphorylation levels of Akt1 and Akt2 in prostate tumor cells. Figure S5 demonstrates a critical role of p21 in Akt2-mediated cell cycle progression. Figure S6 shows that Bax does not play a role in Akt2-mediated spheroid survival. Figure S7 shows the volume of individual tumors measured in the xenograft studies for Fig. 6A |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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