Norovirus GII-4 Causes a More Severe Gastroenteritis Than Other Noroviruses in Young Children
| Autor: | Evelin D. Szakal, Oona Valve, Vesna Blazevic, Leena Puustinen, Heini Huhtala, Timo Vesikari, Marjo Salminen, Leena Huhti |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Genotype
viruses medicine.disease_cause Major Articles and Brief Reports fluids and secretions stomatognathic system medicine Immunology and Allergy Humans Caliciviridae Infections Norovirus GII biology Virulence Norovirus Outbreak virus diseases Infant biology.organism_classification bacterial infections and mycoses Virology Caliciviridae Gastroenteritis Diarrhea Infectious Diseases Vomiting Seasons medicine.symptom |
| Popis: | Norovirus (NoV) GII-4 has emerged as the predominant NoV genotype in outbreaks of gastroenteritis worldwide. We determined clinical features of NoV GII-4 associated acute gastroenteritis (AGE) in comparison with AGE associated with other NoV types in infants during seasons 2001 and 2002. During the prospective follow-up period, 128 primary infections of AGE due to NoV were identified in 405 infants; of these, GII-4 was found in 40 cases (31%). NoV GII-4 was associated with longer duration of diarrhea and vomiting than other NoV genotypes, suggesting greater virulence of NoV GII-4. |
| Databáze: | OpenAIRE |
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