A Precious Diagnostic 'Pearl': The Necklace Pattern in Germ Cell Tumors of the Testis
| Autor: | Juan Miguel Mosquera, Justin T. Snow, Theresa Scognamiglio, Brian D. Robinson, Francesca Khani |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Male
0301 basic medicine Pathology medicine.medical_specialty Adolescent H&E stain Biology engineering.material Pathology and Forensic Medicine Embryonal carcinoma 03 medical and health sciences 0302 clinical medicine Testicular Neoplasms medicine Humans Testicular mass Anatomy Neoplasms Germ Cell and Embryonal medicine.disease Diffuse embryoma 030104 developmental biology medicine.anatomical_structure 030220 oncology & carcinogenesis engineering Immunohistochemistry Surgery Germ cell tumors Pearl Germ cell |
| Zdroj: | International Journal of Surgical Pathology. 26:148-150 |
| ISSN: | 1940-2465 1066-8969 |
| DOI: | 10.1177/1066896917729502 |
| Popis: | Diffuse embryoma is a rare pattern of nonseminomatous germ cell tumor of the testis originally described in 1983. We report a case with this predominant pattern in an 18-year-old male with a painless palpable testicular mass. Although it is relatively common to see a diffuse embryoma pattern focally in mixed nonseminomatous germ cell tumors of the testis, it is rarely the predominant pattern and can represent a diagnostic pitfall on routine hematoxylin and eosin stain. We emphasize the importance of recognizing the individual components within the diffuse embryoma pattern, review the literature, and briefly discuss the ancillary immunohistochemical stains that may be utilized to help support the diagnosis. |
| Databáze: | OpenAIRE |
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