Recommendations for the Empirical Treatment of Complicated Urinary Tract Infections Using Surveillance Data on Antimicrobial Resistance in the Netherlands

Autor: Koningstein, M., A.K. van der bij, Kraker, M.E.A. de, Monen, J.C., Muilwijk, J., Greeff, S.C. de, Geerlings, S.E., Leverstein-van Hall, M.A., ISIS-AR Study Grp
Přispěvatelé: AII - Amsterdam institute for Infection and Immunity, APH - Amsterdam Public Health, Infectious diseases
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Bacterial Diseases
Male
Non-Clinical Medicine
Klebsiella pneumoniae
Epidemiology
Cephalosporin
lcsh:Medicine
Medicine
lcsh:Science
Netherlands
Multidisciplinary
biology
Drug Resistance
Microbial
Antimicrobial
Hospitals
Bacterial Pathogens
Anti-Bacterial Agents
Infectious Diseases
Urinary Tract Infections
Epidemiological Monitoring
Gentamicin
Female
medicine.drug
Research Article
medicine.medical_specialty
Health Planning Guidelines
medicine.drug_class
Mechanisms of Resistance and Susceptibility
Urology
Microbial Sensitivity Tests
Microbiology
Infectious Disease Epidemiology
Antibiotic resistance
Internal medicine
Virology
Humans
Intensive care medicine
Biology
Probability
Treatment Guidelines
Health Care Policy
Population Biology
Bacteria
business.industry
Genitourinary Infections
lcsh:R
Amoxicillin
biology.organism_classification
Enterococcus
Infectious disease (medical specialty)
lcsh:Q
business
Zdroj: PLoS ONE, 9(1)
PLoS ONE, Vol 9, Iss 1, p e86634 (2014)
PLoS ONE
PLoS ONE, 9(1). Public Library of Science
Popis: Background Complicated urinary tract infections (c-UTIs) are among the most common nosocomial infections and a substantial part of the antimicrobial agents used in hospitals is for the treatment of c-UTIs. Data from surveillance can be used to guide the empirical treatment choices of clinicians when treating c-UTIs. We therefore used nation-wide surveillance data to evaluate antimicrobial coverage of agents for the treatment of c-UTI in the Netherlands. Methods We included the first isolate per patient of urine samples of hospitalised patients collected by the Infectious Disease Surveillance Information System for Antibiotic Resistance (ISIS-AR) in 2012, and determined the probability of inadequate coverage for antimicrobial agents based on species distribution and susceptibility. Analyses were repeated for various patient groups and hospital settings. Results The most prevalent bacteria in 27,922 isolates of 23,357 patients were Escherichia coli (47%), Enterococcus spp. (14%), Proteus mirabilis (8%), and Klebsiella pneumoniae (7%). For all species combined, the probability of inadequate coverage was
Databáze: OpenAIRE
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