Double Hematological and Cardiologic Benefits of Autologous Stem Cell Transplantation in a Case of stage III B IgG Myeloma multiplex and Dilatative Cardiomyopathy – a Case Report
| Autor: | Benedek Lazar Erzsebet, I. Benedek, Kopeczi Judit Beata, Jakab Szende, Tatar Cristina Maria, I. Tilea |
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| Rok vydání: | 2015 |
| Předmět: |
IgG myeloma
Pathology medicine.medical_specialty business.industry mega-dose of stem cells Cardiomyopathy medicine.disease General Biochemistry Genetics and Molecular Biology autologous transplantation multiple myeloma Autologous stem-cell transplantation cardiovascular system medicine Medicine Multiplex dilatative cardiomyopathy Stage (cooking) business |
| Zdroj: | ARS Medica Tomitana, Vol 21, Iss 4, Pp 223-226 (2015) |
| ISSN: | 1841-4036 |
| DOI: | 10.1515/arsm-2015-0050 |
| Popis: | We present a case of a 51 year old multiple myeloma patient due to the complexity of his disease. After prior high dose therapy with cardiotoxic cytostatic drugs patient developed cardiac arrest due to a ventricular fibrillation. Cardiopulmonary resuscitation was successfully but the hematologist stopped the cytostatic treatment due to the high cardiac risk. The only way to control his myeloma was an autologous transplantation but this also had a very high cardiotoxic potential due to the high dose of Melphalan administered as conditioning treatment. We present the difficulties and the results of this complex case. It also arises the potential beneficial effects of the megadose of stem cells on the myocardium but this needs further studies. |
| Databáze: | OpenAIRE |
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