Innate immune responses to Listeria in vivo
| Autor: | Sylvain Levallois, Olivier Disson, Claire Maudet, Marc Lecuit |
|---|---|
| Přispěvatelé: | Biologie des Infections - Biology of Infection, Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Paris (UP), Centre National de Référence Listeria - National Reference Center Listeria (CNRL), Centre collaborateur de l'OMS Listeria / WHO Collaborating Centre Listeria (CC-OMS / WHO-CC), Institut Pasteur [Paris]-Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO), CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service des Maladies infectieuses et tropicales [CHU Necker], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Imagine - Institut des maladies génétiques (IHU) (Imagine - U1163), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP), Research in the Biology of Infection Unit is supported financially by Institut Pasteur, Inserm, ANR and ERC, Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Paris Cité (UPCité), Institut Pasteur [Paris] (IP)-Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité) |
| Rok vydání: | 2021 |
| Předmět: |
Microbiology (medical)
[SDV]Life Sciences [q-bio] Placenta Biology medicine.disease_cause Microbiology 03 medical and health sciences Listeria monocytogenes [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases Pregnancy In vivo medicine Humans Listeriosis Pathogen 030304 developmental biology 0303 health sciences Innate immune system 030306 microbiology medicine.disease biology.organism_classification [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology Immunity Innate 3. Good health [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology Infectious Diseases Blood-Brain Barrier Bacteremia Host-Pathogen Interactions Immunology Listeria Female [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology |
| Zdroj: | Current Opinion in Microbiology Current Opinion in Microbiology, Elsevier, 2021, 59, pp.95-101. ⟨10.1016/j.mib.2020.11.006⟩ Current Opinion in Microbiology, 2021, 59, pp.95-101. ⟨10.1016/j.mib.2020.11.006⟩ |
| ISSN: | 1369-5274 |
| Popis: | International audience; Listeria monocytogenes (Lm) is a foodborne bacterial pathogen that causes listeriosis, a severe infection that manifests as bacteremia and meningo-encephalitis mostly in immunocompromised individuals, and maternal-fetal infection. A critical pathogenic determinant of Lm relies on its ability to actively cross the intestinal barrier, disseminate systemically and cross the blood-brain and placental barriers. Here we illustrate how Lm both evades innate immunity, favoring its dissemination in host tissues, and triggers innate immune defenses that participate to its control. |
| Databáze: | OpenAIRE |
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