First Experience Addressing the Prognostic Utility of Novel Urinary Biomarkers in Patients with COVID-19

Autor:	Jeffrey Dahlen, Abira Usman, Naval Walia, Christophe Jerjian, Alastair Cho, Paul A. Gurbel, Malina Traianova, Udaya S. Tantry, Gordon Ens, Kevin P. Bliden
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Oncology medicine.medical_specialty Coronavirus disease 2019 (COVID-19) Urinary system Urine 030204 cardiovascular system & hematology Fatty acid-binding protein urinary 11-dehydro- thromboxane B2 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine medicine Deoxyguanosine In patient 030212 general & internal medicine liver-type fatty acid binding protein Adverse effect urinary 8-hydroxy-2' -deoxyguanosine business.industry Brief Report 8-Hydroxy-2'-deoxyguanosine COVID-19 Infectious Diseases AcademicSubjects/MED00290 chemistry lipids (amino acids peptides and proteins) business
Zdroj:	Open Forum Infectious Diseases
ISSN:	2328-8957
Popis:	Urine 11-dehydro-thromboxane B2 (u11-dh-TxB2), 8-hydroxy-2’-deoxyguanosine (8-OHdG), and liver-type fatty acid binding protein levels (L-FABP) at the time of hospitalization were higher in coronavirus disease 2019 (COVID-19) patients with adverse events vs without events. Higher u11-dh-TxB2 and L-FABP levels were associated with longer hospitalization, more thrombotic events, and greater mortality, providing evidence for potential utility as early prognostic biomarkers for COVID-19.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6660e9279e47593c55e201cc137b528d http://europepmc.org/articles/PMC8194603 Zobrazit plný text záznamu