Characterization of central venous catheter–associated deep venous thrombosis in infants

Autor: Lauren Stephens, Robert A. Drongowski, Brian W. Gray, George B. Mychaliska, Kavita Warrier, Steven W. Pipe, Raquel Gonzalez
Rok vydání: 2012
Předmět:
Zdroj: Journal of Pediatric Surgery. 47:1159-1166
ISSN: 0022-3468
DOI: 10.1016/j.jpedsurg.2012.03.043
Popis: Deep venous thrombosis (DVT) is a frequent complication in infants with central venous catheters (CVCs). We performed this study to identify risk factors and risk-reduction strategies of CVC-associated DVT in infants.Infants younger than 1 year who had a CVC placed at our center from 2005 to 2009 were reviewed. Patients with ultrasonically diagnosed DVT were compared to those without radiographic evidence.Of 333 patients, 47% (155/333) had femoral, 33% (111/333) had jugular, and 19% (64/333) had subclavian CVCs. Deep venous thromboses occurred in 18% (60/333) of patients. Sixty percent (36/60) of DVTs were in femoral veins. Femoral CVCs were associated with greater DVT rates (27%; 42/155) than jugular (11%; 12/111) or subclavian CVCs (9%; 6/64; P.01). There was a 16% DVT rate in those with saphenofemoral Broviac CVCs vs 83% (20/24) in those with percutaneous femoral lines (P.01). Multilumen CVCs had higher DVT rates than did single-lumen CVCs (54% vs 6%, P.01), and mean catheter days before DVT diagnosis was shorter for percutaneous lines than Broviacs (13 ± 17 days vs 30 ± 37 days, P = .02). Patients with +DVT had longer length of stay (86 ± 88 days vs 48 ± 48 days, P.01) and higher percentage of intensive care unit admission (82% vs 70%, P = .02).Deep venous thrombosis reduction strategies in infants with CVCs include avoiding percutaneous femoral and multilumen CVCs, screening percutaneous lines, and early catheter removal.
Databáze: OpenAIRE