Successful Medical Management of Life-threatening Hepatic Hemangioma in Neonates
| Autor: | Shellie Josephs, Joyce M.C. Teng, Ramrada Lekwuttikarn |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
Hepatic Hemangioma Pediatrics medicine.medical_specialty Vasodilator Agents medicine.medical_treatment MEDLINE Propranolol Liver transplantation Methylprednisolone Asymptomatic 03 medical and health sciences Hepatic Artery 0302 clinical medicine Pharmacotherapy 030225 pediatrics medicine Humans Embolization Glucocorticoids Sirolimus business.industry Liver Neoplasms Infant Newborn Embolization Therapeutic Pediatrics Perinatology and Child Health Drug Therapy Combination Female medicine.symptom Hemangioma business medicine.drug |
| Zdroj: | Pediatrics. 144 |
| ISSN: | 1098-4275 0031-4005 |
| DOI: | 10.1542/peds.2019-1339 |
| Popis: | Hepatic hemangioma (HH) is a common asymptomatic, self-limiting benign vascular tumor of the liver in neonates. Although complicated HHs are rare, they have significant risks of morbidity and mortality, especially during the perinatal period. Because of the high risks of complications from surgical interventions, there is an unmet need for effective medical therapy. We report 2 neonates with life-threatening HH who were evaluated for a liver transplant before being treated successfully with combined medical therapy, which included sirolimus, corticosteroids, and propranolol. |
| Databáze: | OpenAIRE |
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