Twin Peaks: A spatial and temporal study of twinning rates in Brazil
| Autor: | Lavinia Schuler-Faccini, Marcelo Zagonel de Oliveira, Juliano André Boquett, Augusto César Cardoso-dos-Santos, Sidia M. Callegari-Jacques, Ursula da Silveira Matte, Maria Teresa Vieira Sanseverino, Márcia Helena Barbian |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
0301 basic medicine Embryology Wilcoxon signed-rank test Maternal Health Twins lcsh:Medicine Geographical Regions Assisted Reproductive Technology Geographical locations Labor and Delivery 0302 clinical medicine Medicine and Health Sciences Public and Occupational Health Gêmeos lcsh:Science education.field_of_study 030219 obstetrics & reproductive medicine Multidisciplinary Geography Singleton Obstetrics and Gynecology Middle Aged Female Live birth Developed country Brazil Research Article Adult Population Developing country Young Adult 03 medical and health sciences Spatio-Temporal Analysis Population Metrics Humans Human Development Index education Socioeconomic status Análise de séries temporais Índice de Desenvolvimento Humano Population Biology Embryos lcsh:R Parturition Biology and Life Sciences South America Birth Rates Regional Geography 030104 developmental biology Birth Earth Sciences Women's Health lcsh:Q People and places Developmental Biology Demography |
| Zdroj: | Repositório Institucional da UFRGS Universidade Federal do Rio Grande do Sul (UFRGS) instacron:UFRGS PLoS ONE, Vol 13, Iss 7, p e0200885 (2018) PLoS ONE |
| ISSN: | 1932-6203 |
| Popis: | Twin births are an important public health issue due to health complications for both mother and children. While it is known that contemporary factors have drastically changed the epidemiology of twins in certain developed countries, in Brazil, relevant data are still scarce. Thus, we carried out a population-based study of live births in spatial and temporal dimensions using data from Brazil's Live Birth Information System, which covers the entire country. Over 41 million births registered between 2001 and 2014 were classified as singleton, twin or multiple. Twinning rates (TR) averaged 9.41 per 1,000 for the study period and a first-order autoregressive model of time-series analysis revealed a global upward trend over time; however, there were important regional differences. In fact, a Cluster and Outlier Analysis (Anselin Local Moran's I) was performed and identified clusters of high TR in an area stretching from the south of Brazil's Northeast Region to the South Region (Global Moran Index = 0.062, P < 0.001). Spearman's correlation coefficient and a Wilcoxon matched pairs test revealed a positive association between Human Development Index (HDI) and TRs in different scenarios, suggesting that the HDI might be an important indicator of childbearing age and assisted reproduction techniques in Brazil. Furthermore, there was a sharp increase of 26.42% in TR in women aged 45 and over during study period. The upward temporal trend in TRs is in line with recent observations from other countries, while the spatial analysis has revealed two very different realities within the same country. Our approach to TR using HDI as a proxy for underlying socioeconomic changes can be applied to other developing countries with regional inequalities resembling those found in Brazil. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|