Prevalence of Vaccine Type Infections in Vaccinated and Non-Vaccinated Young Women: HPV-IMPACT, a Self-Sampling Study
| Autor: | Emmanuel Kabengele, Patrick Petignat, Charlotte de Pree, Mona Aicha Amadane, Pierre Vassilakos, Manuella Viviano, Emilien Jeannot |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Hpv genotypes Adult medicine.medical_specialty HPV Adolescent Health Toxicology and Mutagenesis 030106 microbiology Population lcsh:Medicine Article Sampling Studies law.invention 03 medical and health sciences Young Adult 0302 clinical medicine law Internal medicine Prevalence Medicine Humans 030212 general & internal medicine Papillomavirus Vaccines education ddc:613 Female Human papillomavirus 16/isolation & purification Human papillomavirus 18/isolation & purification Immunization Papillomavirus Infections/epidemiology Papillomavirus Infections/prevention & control Papillomavirus Vaccines/administration & dosage Switzerland/epidemiology Vaccination self-sampling vaccination education.field_of_study Human papillomavirus 16 ddc:618 Human papillomavirus 18 business.industry Gardasil lcsh:R Papillomavirus Infections Public Health Environmental and Occupational Health Medical school virus diseases female genital diseases and pregnancy complications Hpv testing Cotton swab business Switzerland medicine.drug Self sampling |
| Zdroj: | International Journal of Environmental Research and Public Health International journal of environmental research and public health, vol. 15, no. 7, pp. 1447 Volume 15 Issue 7 International Journal of Environmental Research and Public Health, Vol. 15, No 7 (2018) International Journal of Environmental Research and Public Health, Vol 15, Iss 7, p 1447 (2018) |
| ISSN: | 1660-4601 1661-7827 |
| Popis: | Background: The human papillomavirus (HPV) vaccination program for young girls aged 11–26 years was introduced in Switzerland in 2008. The objective of this study was to evaluate the prevalence of high- and low-risk HPV in a population of undergraduate students using self-sampling for monitoring the HPV vaccination program’s effect. Methods: Undergraduate women aged between 18–31 years, attending the Medical School and University of Applied Sciences in Geneva, were invited to participate in the study. Included women were asked to perform vaginal self-sampling for HPV testing using a dry cotton swab. Results: A total of 409 students participated in the study—aged 18–31 years—of which 69% of the participants were vaccinated with Gardasil HPV vaccine and 31% did not received the vaccine. About HPV prevalence, 7.2% of unvaccinated women were HPV 16 or 18 positive, while 1.1% of vaccinated women were infected by HPV 16 or 18 (p < 0.01). Prevalence of HPV 6 and 11 was 8.3% in non-vaccinated women versus 2.1% in vaccinated women (p < 0.02). We observed no cross-protection for the other HPV genotypes of a low- and high-risk strain. Conclusions: Prevalence of HPV 6/11/16/18 was lower in vaccinated women versus unvaccinated women. Continued assessment of HPV vaccine effectiveness in real population is needed. |
| Databáze: | OpenAIRE |
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