Monitoring PDT effects in basal cell carcinoma treatment using thermal imaging
| Autor: | Sebastian Kwiatek, Aleksander Sieroń, Karolina Sieroń, Łukasz Kapek, Agnieszka Szurko, Agata Stanek, Armand Cholewka |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Skin Neoplasms medicine.medical_treatment Biophysics Photodynamic therapy Dermatology Lesion Skin tumours Medicine Humans Pharmacology (medical) Basal cell carcinoma Angiology Skin Photosensitizing Agents business.industry Aminolevulinic Acid medicine.disease Radiation therapy Oncology Photochemotherapy Male patient Carcinoma Basal Cell Cancer cell Radiology medicine.symptom business |
| Zdroj: | Photodiagnosis and photodynamic therapy. 31 |
| ISSN: | 1873-1597 |
| Popis: | Background One of the most frequent type of malignant skin lesion (almost 95 percent of all skin tumours) is basal cell carcinoma (BCC). It is often treated by radiotherapy using ionizing radiation as well by photodynamic therapy (PDT) which is a selective method directed only on cancer cells and well tolerated by patients. Materials and methods Eight male patients of the Department and Clinic of Internal Diseases, Angiology and Physical Medicine in Bytom, Medical University of Silesia, in Katowice, Poland suffering from basal cell carcinoma were monitored by thermovision during the photodynamic therapy. All lesions were diagnosed as superficial were confirmed by histopathological examination. Results The dynamics of changes observed in the isotherm area during the therapy can provide physicians with additional information. The significant increase of observed isotherm area in comparison to the lesion area diagnosed by a physician was confirmed, which may be connected with the increased metabolism processes occurring in the tissue surrounded the lesion. Conclusion The obtained results based on the temperature gradient changes in the lesion vicinity area may bring some new information describing the range of biochemical and physiological processes occurring during photodynamic therapy. |
| Databáze: | OpenAIRE |
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