Efficacy, safety, and predictability of transepithelial photorefractive keratectomy: meta-analysis
| Autor: | Stefan Wagenpfeil, Navid Ardjomand, Achim Langenbucher, Elias Flockerzi, Alexandra Sabau, Abdelshafi Behkit, Berthold Seitz, Loay Daas |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Visual Acuity MEDLINE Astigmatism Refraction Ocular Photorefractive Keratectomy law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law Germany Internal medicine medicine Humans Prospective Studies Predictability Prospective cohort study Retrospective Studies business.industry medicine.disease Sensory Systems Photorefractive keratectomy Confidence interval Ophthalmology Treatment Outcome Meta-analysis 030221 ophthalmology & optometry Lasers Excimer Surgery business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Cataract and Refractive Surgery. 47:634-640 |
| ISSN: | 1873-4502 0886-3350 |
| DOI: | 10.1097/j.jcrs.0000000000000487 |
| Popis: | Purpose The aim of this study was to evaluate the efficacy, safety and predictability of transepithelial photorefractive keratectomy (TransPRK) for correcting myopia, astigmatism and hyperopia. Setting Department of Ophthalmology, Saarland University Medical Center, Homburg/Saar, Germany DESIGN:: Meta-analysis of retrospective or prospective studies METHODS:: Relevant studies were collected from Medline and included when meeting the following predefined criteria: randomized controlled trials, at least one of main outcome measures efficacy, safety or predictability and one common TRPK laser ("Schwind Amaris"). The parameters estimates and 95% confidence intervals (CI) were derived from random-effects meta-analysis to account for possible heterogeneity. Results Since hyperopia studies did not meet the inclusion criteria, the results are centered around myopia and astigmatism. Sixteen studies with a total of 1,924 treated eyes were included in the meta-analysis. The mean efficacy, safety and predictability had a probability of 94% CI=0.86-0.97, 0% CI= 0.00-0.03 and 89% CI=0.82-0.93, respectively. The mean correction index, difference vector and index of success had a value of 1.01 CI=1.01-1.02, 0.2 CI=0.06-0.34 and 0.12 CI=0.07-0.18, respectively. Conclusion This summary estimate shows that the TransPRK is highly effective, safe and predictable in correcting myopia and/or astigmatism. |
| Databáze: | OpenAIRE |
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