A case of early onset normotensive scleroderma renal crisis in a patient with diffuse cutaneous systemic sclerosis
| Autor: | Steven Gambert, Jason S. Javillo, Hany Bashandy |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
medicine.medical_specialty
Systemic disease Pathology Biopsy Scleroderma Renal Crisis Kidney Gastroenterology Scleroderma Diagnosis Differential chemistry.chemical_compound Fatal Outcome Internal medicine medicine Humans Skin Creatinine Scleroderma Systemic business.industry General Medicine Microangiopathic hemolytic anemia Middle Aged medicine.disease Prognosis Connective tissue disease medicine.anatomical_structure chemistry Disease Progression Female Kidney Diseases Age of onset business |
| Zdroj: | Southern medical journal. 99(8) |
| ISSN: | 0038-4348 |
| Popis: | Scleroderma renal crisis (SRC) has classically been defined as a new onset of accelerated arterial hypertension associated with a rapid increase in serum creatinine concentration and/or microangiopathic hemolytic anemia. SRC occurs in approximately 20% of patients with systemic sclerosis who have diffuse cutaneous manifestations. In addition, 10% of reported cases of SRC with diffuse cutaneous involvement have normal blood pressures; in the majority of these cases, SRC occurs after treatment with corticosteroids. We describe a patient who presented with an early onset SRC in the setting of diffuse cutaneous systemic sclerosis in evolution without prior accelerated arterial hypertension or corticosteroid use. |
| Databáze: | OpenAIRE |
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