Influence of cadmium on two-kidney Goldblatt hypertension in Dahl rats

Autor: Martha Heine, Edward V. Ohanian, Junichi Iwai
Rok vydání: 1978
Předmět:
Zdroj: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 158(3)
ISSN: 0037-9727
Popis: In Dahl hypertension-resistant (R) and hypertension-sensitive (S) lines of rats, an ip cadmium injection exacerbated two-kidney Goldblatt hypertension and mortality in S but not in R rats. Renal and hepatic cadmium concentrations of S rats were markedly higher than those of R rats. These observations imply that the genetic background critically affects the adverse effects of cadmium on two-kidney Goldblatt hypertension in Dahl rats.
Databáze: OpenAIRE