Antibiotic use in pre-school children and the correlation with adult educational levels in two Nordic counties:a replication of a 20-year-old study
| Autor: | Jette Nygaard Jensen, Stina Ivarsson, Katarina Hedin, Anne Thorsted, Mia Tyrstrup, Helle Neel Jakobsen, Emma Brogaard, Magnus Arpi, Matilde Bøgelund Hansen, Eva Melander |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
0301 basic medicine Microbiology (medical) medicine.medical_specialty 030106 microbiology Drug Prescriptions Antibiotic prescribing Antibiotic prescription Antimicrobial Stewardship Young Adult 03 medical and health sciences 0302 clinical medicine children Replication (statistics) Humans Medicine 030212 general & internal medicine Antibiotic use Child skin and connective tissue diseases Sweden ecological study General Immunology and Microbiology business.industry Ecological study General Medicine Drug Utilization Anti-Bacterial Agents Infectious Diseases Child Preschool Family medicine Pre school sense organs business |
| Zdroj: | Hansen, M B, Thorsted, A B, Ivarsson, S, Tyrstrup, M, Hedin, K, Melander, E, Arpi, M, Jakobsen, H N, Brogaard, E & Jensen, J N 2021, ' Antibiotic use in pre-school children and the correlation with adult educational levels in two Nordic counties : a replication of a 20-year-old study ', Infectious Diseases, vol. 53, no. 4, pp. 281-290 . https://doi.org/10.1080/23744235.2021.1882696 |
| DOI: | 10.1080/23744235.2021.1882696 |
| Popis: | Objective: The aim of this study was to describe the change of antibiotic prescribing in pre-school children in the municipalities of the former Copenhagen County in Denmark and Skåne County in Sweden after 20 years of antibiotic stewardship effort. Furthermore, the variation in the prescribing of antibiotics between the municipalities and the correlation between municipal adult educational level and antibiotic prescribing in pre-school children was assessed. Methods: In this ecological study, information on antibiotic prescribing in pre-school children was obtained from a central pharmacy settlement system in each Region. The antibiotic prescribing rate was expressed in defined daily doses per 1,000 inhabitants per day (DDD/TID) and number of prescriptions/1000 inhabitants. Information on municipal adult educational levels was obtained from Statistics Denmark and Statistics Sweden. Results: The antibiotic prescribing rate during 2017 was higher in the municipalities of Copenhagen County (5.6–7.9 DDD/TID) compared to the municipalities of Skåne County (4.2–6.6 DDD/TID). In 1998 a higher rate was found in Skåne County (9.6–17.7 DDD/TID) compared to Copenhagen County (8.0–12.9 DDD/TID). A non-significant negative correlation between adult educational levels and antibiotic prescribing was observed in the municipalities of Copenhagen County (r= −0.233, p =.352) while the correlation was positive in the municipalities of Skåne County (r= +0.410, p =.018). The same correlations were observed in 1998. Conclusion: We found higher antibiotic prescribing in pre-school children in the municipalities of Copenhagen County compared to Skåne County in 2017, suggesting a possible overuse of antibiotics in Denmark. Further research should try to elucidate the reasons for the observed variation. |
| Databáze: | OpenAIRE |
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