Computed tomography-based three-dimensional dosimetry of intracavitary brachytherapy for cervical cancer
| Autor: | Yoshio Monzen, Taichi Kurose, Mio Mito, Koichi Wadasaki, Hajime Okazaki |
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| Rok vydání: | 2010 |
| Předmět: |
Adult
medicine.medical_specialty medicine.medical_treatment Brachytherapy Uterine Cervical Neoplasms Computed tomography Three dimensional dosimetry Imaging Three-Dimensional medicine Humans Dosimetry Radiology Nuclear Medicine and imaging Radiometry Aged Aged 80 and over Cervical cancer medicine.diagnostic_test business.industry Radiotherapy Planning Computer-Assisted Intracavitary brachytherapy Radiotherapy Dosage Middle Aged medicine.disease Radiation therapy Tomography x ray computed Female Radiology Tomography X-Ray Computed Nuclear medicine business |
| Zdroj: | Japanese Journal of Radiology. 28:740-745 |
| ISSN: | 1867-108X 1867-1071 |
| Popis: | The aim of this study was to show the results of computed tomography (CT)-based dosimetry of intracavitary brachytherapy for cervical cancer.A total of 20 patients with cervical cancer underwent intracavitary brachytherapy with external beam radiation therapy. The prescribed dose of brachytherapy was 6 Gy per fraction to point A. In every fraction a CT scan was performed after applicator insertion and three-dimensional (3D) dosimetry was done. The tumor dose was evaluated using D90 (the minimum dose delivered to 90% of the volume), and the doses of risk organs were evaluated using D2cc (the minimum dose in the most irradiated 2 cm3 of the volume).The mean D90 for the clinical target volume (CTV) was 7.0 Gy (range 4.8-9.8 Gy). There was a negative correlation between the volume and the D90 for the CTV. The mean D2cc doses for the rectum and bladder were 6.0 Gy (range 3.9-9.0 Gy) and 6.5 Gy 5 Gy 2.9-9.0 Gy), respectively.CT-based 3D dosimetry of intracavitary brachytherapy for cervical cancer was useful for evaluating the doses of the CTV and the organs at risk. In cases with a large CTV, CTV D90 was often lower than the point A dose, and modulation of the prescribed dose might have to be considered. |
| Databáze: | OpenAIRE |
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