Basic study on a lower-energy defibrillation method using computer simulation and cultured myocardial cell models
| Autor: | Hidehiro Hosaka, T. Iwasaka, A. Yaguchi, Masato Odagaki, M. Ishikawa, K. Nagase |
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| Rok vydání: | 2007 |
| Předmět: |
Fibrillation
Mice Inbred ICR Electric shock Defibrillation Computer science medicine.medical_treatment Cardiac muscle Electric Countershock medicine.disease Models Biological Lower energy Cardiovascular physiology Mice medicine.anatomical_structure Fetus Spiral wave medicine Myocardial cell Animals Computer Simulation Myocytes Cardiac medicine.symptom Simulation Cells Cultured Biomedical engineering |
| Zdroj: | EMBC (Supplement) |
| ISSN: | 1557-170X |
| Popis: | Computer simulation and myocardial cell models were used to evaluate a low-energy defibrillation technique. A generated spiral wave, considered to be a mechanism of fibrillation, and fibrillation were investigated using two myocardial sheet models: a two-dimensional computer simulation model and a two-dimensional experimental model. A new defibrillation technique that has few side effects, which are induced by the current passing into the patient's body, on cardiac muscle is desired. The purpose of the present study is to conduct a basic investigation into an efficient defibrillation method. In order to evaluate the defibrillation method, the propagation of excitation in the myocardial sheet is measured during the normal state and during fibrillation, respectively. The advantages of the low-energy defibrillation technique are then discussed based on the stimulation timing. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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