Cerebrospinal fluid β2-microglobulin in neurological disorders
| Autor: | J. Kovanen, Matti Iivanainen, R. Tenhunen |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male Nervous system medicine.medical_specialty Pathology Neurology Adolescent Central nervous system Beta-Globulins 03 medical and health sciences 0302 clinical medicine Cerebrospinal fluid Humans Medicine Outpatient clinic Meningitis Aged 030304 developmental biology Paresis 0303 health sciences business.industry Beta-2 microglobulin Peripheral Nervous System Diseases Cerebrospinal Fluid Proteins Cerebral Infarction General Medicine Middle Aged medicine.disease 3. Good health medicine.anatomical_structure Encephalitis Female Neurology (clinical) Nervous System Diseases medicine.symptom beta 2-Microglobulin business Polyneuropathy 030217 neurology & neurosurgery |
| Zdroj: | Acta Neurologica Scandinavica. 58:366-373 |
| ISSN: | 1600-0404 0001-6314 |
| DOI: | 10.1111/j.1600-0404.1978.tb02901.x |
| Popis: | Beta-2-microglobulin was measured in specimens of cerebrospinal fluid (CSF) collected from 167 patients classified in 14 diagnostic categories at an outpatient Department of Neurology. In the control group of 29 subjects without any obvious disease of the nervous system, the concentration of beta-2-microglobulin was 1.15 +/- 0.37 mg/1 (M +/- s.d.). The concentration was almost significantly elevated in the groups with fresh brain infarct, central nervous system infection, and polyneuropathy. The serum concentrations of beta-2-microglobulin did not differ significantly among these diagnostic categories. The mean ratio between CSF and serum beta-2-microglobulin was 0.79 +/- 0.32 in the control group and more than 1.0 in the patients with brain infarcts, CNS infections and spinal paresis, but the differences were not statistically significant. |
| Databáze: | OpenAIRE |
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