Handedness, immune disorders and information bias
| Autor: | A. Kahan, Georges Dellatolas, M.F. Kahn, Michel Chavance, M.G. Bousser, J.P. Le Floch, G. Tchobroutsky, B. Amor, B. Grardel |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
Male Cognitive Neuroscience Migraine Disorders Population Experimental and Cognitive Psychology Disease Functional Laterality Developmental psychology Autoimmune Diseases Behavioral Neuroscience Bias Risk Factors Immunopathology medicine Humans Lupus Erythematosus Systemic Information bias education education.field_of_study Case-control study Middle Aged medicine.disease Graves Disease Diabetes Mellitus Type 1 Migraine Case-Control Studies Laterality Conviction Female Psychology Clinical psychology |
| Zdroj: | Neuropsychologia. 28(5) |
| ISSN: | 0028-3932 |
| Popis: | In order to investigate the relations between handedness and migraine or immune disorders, we performed a case control study comparing the handedness of patients suffering from systemic lupus erythematosus (SLE), type I diabetes, Graves' disease, or migraine to that of a random sample of controls from the general population. A handedness index was measured from a 10-item questionnaire. No significant difference was observed. But when the controls who denied having ever suffered from migraine or any allergic disease were set apart from those who gave at least one positive answer to the same questions, the former were found more right-handed, i.e. with a lower handedness index than the latter (P less than 0.05) and than the SLE patients (P less than 0.05). More generally, the mean observed handedness index of controls giving a positive answer to any question about their health was found repeatedly higher than that of controls giving a negative answer: this was observed for 27 of the 32 questions. These results are highly suggestive of an information bias, the subjects saying they use the right hand for each of the 10 activities considered in the questionnaire being more likely to deny having suffered from a given disease or used, more or less recently, some drug or medical service. Our conviction is that previous observations dealing with the same topic are also more easily explained by the presence of an information bias than by Geschwind's theory. The implications for the design of further epidemiologic studies are discussed. |
| Databáze: | OpenAIRE |
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