Centralized preparation of hazardous drugs

Autor: P. Larrouturou, M. C. Taugourdeau, J. Huchet
Rok vydání: 1992
Předmět:
Zdroj: Pharmaceutisch Weekblad Scientific Edition. 14:88-92
ISSN: 1573-739X
0167-6555
DOI: 10.1007/bf01962692
Popis: In 1987, the manager of the Saint-Joseph Hospital (Paris, France) requested a reorganization of cytotoxic drug preparation. Protection for staff who handle hazardous drugs was the main concern. The conclusions drawn from a first analysis emphasize the advantages of a centralized reconstitution unit against a decentralized system. Subsequently, a workload study and an economic study (investment, maintenance, supplies, staff costs, comparative balance sheet and a 5-year simulation) were carried out, but to choose between a laminar airflow in aseptic room and an isolator in a conventional room. The selected isolator is the first of the conception: the central half-suit uses as a server, and four sleeves located on one side allow two technicians to work in a sterile and closed area without sterile garments.
Databáze: OpenAIRE