Camellia (Camellia oleifera Abel.) seed oil promotes milk fat and protein synthesis‐related gene expression in bovine mammary epithelial cells
| Autor: | Jing Zhang, Xinlu Liu, Xian-Dong Liao, Wanqi Zhong, Yongcheng Jin, Jinglin Shen, Changhai Zhou |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Camellia oleifera lcsh:TX341-641 P70-S6 Kinase 1 casein fatty acids 03 medical and health sciences chemistry.chemical_compound Protein kinase A protein expression Fatty acid synthesis Original Research biology Activator (genetics) 0402 animal and dairy science food and beverages mRNA expression 04 agricultural and veterinary sciences biology.organism_classification camellia seed oil 040201 dairy & animal science Molecular biology Sterol regulatory element-binding protein Fatty acid synthase 030104 developmental biology chemistry bovine mammary epithelial cells Ribosomal protein s6 biology.protein lcsh:Nutrition. Foods and food supply Food Science |
| Zdroj: | Food Science & Nutrition Food Science & Nutrition, Vol 8, Iss 1, Pp 419-427 (2020) Food Science & Nutrition, 8(1):419-427 |
| ISSN: | 2048-7177 |
| Popis: | Camellia (Camellia oleifera Abel.) seed oil is a commonly used edible oil of China. In ancient Chinese literature, it is mentioned to be helpful for postpartum repair and lactation in women. Research on camellia seed oil (CO) as a feed additive for dairy cattle is less. We investigated the effect of CO on the expression of milk fat and protein syntheses‐related genes in differentiated bovine mammary epithelial cells (MAC‐T) using soybean oil (SO) as the control. The results showed that CO increased the expression of genes related to de novo synthesis of fatty acids including sterol regulatory element‐binding protein 1 (SREBP1), acetyl‐CoA carboxylase 1 (ACC), fatty acid synthase (FASN), lipoprotein lipase (LPL), and stearoyl‐CoA desaturase (SCD) (p Camellia (Camellia oleifera Abel.) seed oil activated genes related to de novo synthesis of fatty acids through SERBP1 signaling pathway and promoted the synthesis of β‐casein through PI3K‐AKT‐mTOR‐S6K1 and JAK2‐STAT5 signaling pathways. |
| Databáze: | OpenAIRE |
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