A novel complex t(2;5;13)(p23;q35;q14) in small cell variant type anaplastic large cell lymphoma with peripheral involvement

Autor:	Young Hyeh Ko, Sun-Hee Kim, Jung-Ho Suk, Kihyun Kim, Hyun-Jung Cho, Eun-Young Tak, Sun-Young Kong
Rok vydání:	2004
Předmět:	Adult congenital hereditary and neonatal diseases and abnormalities Cancer Research Cell Chromosomal translocation Biology Translocation Genetic hemic and lymphatic diseases Genetics medicine Anaplastic lymphoma kinase Humans Anaplastic Lymphoma Kinase Molecular Biology Anaplastic large-cell lymphoma In Situ Hybridization Fluorescence medicine.diagnostic_test Variant type Receptor Protein-Tyrosine Kinases Protein-Tyrosine Kinases medicine.disease Peripheral medicine.anatomical_structure Chromosomes Human Pair 2 Karyotyping Cancer research Chromosomes Human Pair 5 Female Lymphoma Large B-Cell Diffuse Fluorescence in situ hybridization
Zdroj:	Cancer genetics and cytogenetics. 154(2)
ISSN:	0165-4608
Popis:	We report the case of a 32-year-old woman who was diagnosed as having small cell variant type anaplastic large cell lymphoma with peripheral involvement. A cytogenetic study showed a complex translocation, t(2;5;13)(p23;q35;q14). Fluorescence in situ hybridization with ALK break-apart probes confirmed that the three-break rearrangement involves the ALK gene.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65eaa46333d9d1ffdf1f28e4a811139a https://pubmed.ncbi.nlm.nih.gov/15474159 Zobrazit plný text záznamu Full Text from ScienceDirect