The route by which antibodies enter the circulation after injection of immune serum into the exocoel of foetal rabbits
| Autor: | Gwynneth P. Hemmings, Francis William Rogers Brambell, W. A. Hemmings, Megan Henderson, W. T. Rowlands |
|---|---|
| Rok vydání: | 1951 |
| Předmět: |
Fetus
biology Immune Sera General Engineering Uterus Embryo Lagomorpha Immune sera Embryonic stem cell Antibodies Injections Andrology medicine.anatomical_structure embryonic structures Immunology medicine biology.protein Animals General Earth and Planetary Sciences Rabbits Antibody Uterine lumen reproductive and urinary physiology General Environmental Science |
| Zdroj: | Proceedings of the Royal Society of London. Series B - Biological Sciences. 138:188-195 |
| ISSN: | 2053-9193 |
| DOI: | 10.1098/rspb.1951.0013 |
| Popis: | Immune sera were injected into the embryonic membranes of foetal rabbits at about 24 days of age. Alternate embryos in each uterus were injected through the uterine wall, the intervening ones remaining as controls. Leakage occurs into the uterine lumen from the punctures. In the case of rabbit serum, the uptake to the foetal circulation is the same in the control, where entry is entirely via the entoderm, as in the injected foetuses, indicating that no entry occurs by way of the mesothelial surface of the splanchnopleur. Antibodies of bovine origin are excluded from the foetal circulation as effectively when the inner, as when the outer, surface of the splanchnopleur is exposed to immune serum, at this stage. |
| Databáze: | OpenAIRE |
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