Thrombocytosis as a Prognostic Factor in Endometrial Carcinoma

Autor: G. Arikan, Fatih Gücer, Olaf Reich, Franz Moser, Josef Haas, Karl Tamussino, Raimund Winter, Edgar Petru
Rok vydání: 1998
Předmět:
Zdroj: Gynecologic Oncology. 70:210-214
ISSN: 0090-8258
Popis: We reviewed the prevalence of thrombocytosis (platelet count >/=400, 000/microL) and its association with outcome in 135 consecutive endometrial carcinoma patients and compared the platelet count with other prognostic factors. Nineteen of 135 patients (14%) had thrombocytosis. Thrombocytosis was significantly more frequent in advanced disease (stage II-IV), unfavorable grade (G2 and G3), deep myometrial invasion, and lymph-vascular space invasion. The overall 5-year survival rate was 92%. The 5-year survival rate of the 19 patients with thrombocytosis was significantly worse than that of the patients without thrombocytosis (61 vs 96%, P < 0.0001). The recurrence rate was significantly higher in patients with thrombocytosis than in those with a platelet count
Databáze: OpenAIRE