Polysaccharide from Artocarpus heterophyllus Lam. (jackfruit) pulp modulates gut microbiota composition and improves short-chain fatty acids production
| Autor: | Kexue Zhu, Chuan Li, Yanjun Zhang, Shaoping Nie, Qibing Liu, Haofei Fan, Fei Xu, Shunjiang Zeng, Gang Wu, Lehe Tan |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Firmicutes
Gut flora Polysaccharide 01 natural sciences Analytical Chemistry Actinobacteria Artocarpus Feces Mice 0404 agricultural biotechnology Polysaccharides RNA Ribosomal 16S Animals Food science chemistry.chemical_classification Tenericutes biology Chemistry 010401 analytical chemistry Bacteroidetes 04 agricultural and veterinary sciences General Medicine biology.organism_classification Fatty Acids Volatile 040401 food science 0104 chemical sciences Gastrointestinal Microbiome Proteobacteria Food Science |
| Zdroj: | Food chemistry. 364 |
| ISSN: | 1873-7072 |
| Popis: | This study aimed to investigate the effects of polysaccharide from Artocarpus heterophyllus Lam. pulp (JFP-Ps) on gut microbiota composition and short-chain fatty acids production in mice. The microbial communities of V3 and V4 region 16S rRNA gene was amplified by PCR, then sequenced on an Illumina MiSeq PE250 platform and analyzed by multivariate statistical methods. The concentrations of short-chain fatty acids (SCFAs) were measured using gas chromatography (GC) equipped with a flame ionization detector (FID). The results showed that JFP-Ps significantly affected the levels of intestinal bacteria, including Bacteroidetes, Firmicutes, Proteobacteria, Cyanobacteria, Actinobacteria, Tenericutes, Deferribacteres and TM7. The concentrations of acetic acid, propionic acid, n-butyric acid and total SCFAs in mouse feces were significantly increased by treatment with JFP-Ps for 2 weeks. These results indicate that JFP-Ps is beneficial to the gut health and can be developed as a functional ingredient in relation to gut health. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect