Occurrence of CA 125 and CA 19-9 Tumor-Associated Antigens in Sera of Patients with Gynecologic, Trophoblastic, and Colorectal Tumors
| Autor: | G. N. Than, I.F. Csaba, P.M. Göcze, K.F. Krommer, D. G. Szabo |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Oncology
medicine.medical_specialty endocrine system diseases Genital Neoplasms Female Trophoblastic Tumor Radioimmunoassay Rectum Ovary Trophoblastic Neoplasms chemistry.chemical_compound Antigen Antigens Neoplasm Pregnancy Internal medicine Biomarkers Tumor medicine Humans Antigens Tumor-Associated Carbohydrate Choriocarcinoma Colorectal Tumors Rectal Neoplasms business.industry Obstetrics and Gynecology Sialyl-Lewis A medicine.disease female genital diseases and pregnancy complications medicine.anatomical_structure Reproductive Medicine chemistry Colonic Neoplasms Uterine Neoplasms Cancer research Female CA19-9 Ovarian cancer business |
| Zdroj: | Gynecologic and Obstetric Investigation. 25:268-272 |
| ISSN: | 1423-002X 0378-7346 |
| Popis: | The present study was undertaken to test the parallel detectability of ovarian cancer antigen CA 125 and gastrointestinal cancer antigen CA 19-9 in the sera of patients with malignant ovarian tumors, benign ovarian tumors, endometrial cancers, cervical cancers, colorectal cancers, and trophoblastic tumors and in early 1st-trimester pregnant as well as in healthy nonpregnant controls. In all kinds of gynecologic and colorectal tumors raised concentrations of both antigens were found with the exception of malignant nonepithelial ovarian tumors where neither of the antigens showed positive reaction. The most positive cases were found in the group with epithelial ovarian cancers. Of the two antigens CA 125 was the more responsive. No positive cases were found with either of the antigens in non-pregnant healthy controls or in patients with benign ovarian tumors. The parallel determination of the two antigens gives us a better opportunity to recognize pelvic tumors and further may enable us to distinguish ovarian and colorectal tumors. |
| Databáze: | OpenAIRE |
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