Short‐term effects of COVID‐19 on semen parameters: A multicenter study of 69 cases
| Autor: | Mehmet Yaris, Ahmet Sanli, Mehmet Hamza Gultekin, Abdullah Erdogan, Guven Erbay, Harun Turel, Ufuk Yavuz, Mehmet Karabakan |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Urology Endocrinology Diabetes and Metabolism medicine.medical_treatment Semen Pathogenesis Disease SARS‐CoV‐2 male infertility Male infertility 03 medical and health sciences Sars-Cov-2 Infection 0302 clinical medicine Endocrinology COVID‐19 Oxygen therapy Internal medicine medicine Humans Spermatogenesis 030219 obstetrics & reproductive medicine SARS-CoV-2 business.industry COVID-19 semen Original Articles Middle Aged medicine.disease Sperm spermatogenesis Pathophysiology Semen Analysis Reproductive Medicine Testicular Involvement Original Article business |
| Zdroj: | Andrology |
| ISSN: | 2047-2927 2047-2919 |
| DOI: | 10.1111/andr.13019 |
| Popis: | Objective COVID‐19, which is known to be caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is a global health problem that can cause multiorgan damage because of its use of the angiotensin‐converting enzyme 2 (ACE2) receptor in its pathophysiology. We aimed to investigate whether SARS‐CoV‐2 had a short‐term effect on spermatogenesis, which plays an important role in male reproductive health as it has abundant ACE2 expression in testicular tissue. Material and methods This multicenter study included 69 patients aged 20–45 years, who admitted to our hospitals between April 2020 and October 2020 with a history of a positive test result for SARS‐CoV‐2 based on the nasopharyngeal or oropharyngeal swab samples and had recovered from the disease at least three months earlier and who had undergone a spermiogram test in the hospital database within the last year before the onset of disease. The patients were divided into two groups according to their COVID‐19 symptoms being mild or moderate, depending on whether they had received home treatment or required hospitalization for oxygen therapy. Semen samples taken before and after COVID‐19 were compared within and between the groups in terms of sperm parameters. Results The mean age of the patients included in the study was 30.4±4.8 years in the mild symptomatic COVID‐19 group and 31.06±4.2 years in the moderate symptomatic group. When the spermiogram samples of the patients before and after COVID‐19 were evaluated, it was found that motility and vitality significantly decreased in the mild symptomatic group, while the decrease in all semen parameters was statistically significant in the moderate symptomatic group. Conclusion Although the mechanism by which COVID‐19 causes testicular involvement remains uncertain, its short‐term results on spermatogenesis reveals that COVID‐19 negatively affects sperm parameters. |
| Databáze: | OpenAIRE |
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