Association between incident falls and subsequent fractures in patients attending the fracture liaison service after an index fracture: a 3-year prospective observational cohort study
| Autor: | Lisanne Vranken, Caroline E Wyers, Robert Y Van der Velde, Heinrich M J Janzing, Sjoerd Kaarsemakers, Johanna Driessen, John Eisman, Jacqueline R Center, Tuan V Nguyen, Thach Tran, Dana Bliuc, Piet Geusens, Joop P van den Bergh |
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| Přispěvatelé: | RS: NUTRIM - R3 - Respiratory & Age-related Health, Interne Geneeskunde, Clinical Pharmacy, RS: Carim - V01 Vascular complications of diabetes and metabolic syndrome, MUMC+: DA KFT Medische Staf (9), RS: CAPHRI - R3 - Functioning, Participating and Rehabilitation, Wyers, Caroline/0000-0001-7662-3990, Vranken, Lisanne, Wyers, Caroline E., Van der Velde, Robert Y., Janzing, Heinrich M. J., Kaarsemakers, Sjoerd, Driessen, Johanna, Eisman, John, Center, Jacqueline R., Nguyen, Tuan, V, Tran , Thach, Bliuc, Dana, GEUSENS, Piet, VAN DEN BERGH, Joop |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Male
1103 Clinical Sciences 1117 Public Health and Health Services 1199 Other Medical and Health Sciences OSTEOPOROSIS 1ST Cohort Studies orthopaedic & trauma surgery Risk Factors HISTORY Humans Prospective Studies OLDER-PEOPLE RECURRENT METAANALYSIS Aged Netherlands general medicine (see Internal Medicine) Incidence HIP FRACTURE MEN General Medicine Middle Aged PREVENTION internal medicine RISK-FACTORS Osteoporosis Accidental Falls Female Osteoporotic Fractures |
| Zdroj: | BMJ Open, 12(7):e058983. BMJ Publishing Group |
| ISSN: | 2044-6055 |
| Popis: | ObjectivesTo evaluate the risk of subsequent fractures in patients who attended the Fracture Liaison Service (FLS), with and without incident falls after the index fracture.DesignA 3-year prospective observational cohort study.SettingAn outpatient FLS in the Netherlands.ParticipantsPatients aged 50+ years with a recent clinical fracture.Outcome measuresIncident falls and subsequent fractures.ResultsThe study included 488 patients (71.9% women, mean age: 64.6±8.6 years). During the 3-year follow-up, 959 falls had been ascertained in 296 patients (60.7%) (ie, fallers), and 60 subsequent fractures were ascertained in 53 patients (10.9%). Of the fractures, 47 (78.3%) were fall related, of which 25 (53.2%) were sustained at the first fall incident at a median of 34 weeks. An incident fall was associated with an approximately 9-fold (HR: 8.6, 95% CI 3.1 to 23.8) increase in the risk of subsequent fractures.ConclusionThese data suggest that subsequent fractures among patients on treatment prescribed in an FLS setting are common, and that an incident fall is a strong predictor of subsequent fracture risk. Immediate attention for fall risk could be beneficial in an FLS model of care.Trial registration numberNL45707.072.13. |
| Databáze: | OpenAIRE |
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